Platelet-rich plasma and platelet-rich fibrin are prepared from a patient's own blood at the point of care, using a kit and a centrifuge. The kit you choose affects consistency, cost per treatment and which centrifuge you need, so it's worth comparing carefully.
This guide explains what's in a kit, how PRP and PRF kits differ, and what to confirm before you order.
What's in a kit
- Blood collection tubes, often with an anticoagulant for PRP; PRF tubes are typically additive-free.
- Transfer devices, syringes and needles for drawing and transferring.
- Some kits include separation gels or specialized tubes that make the process more repeatable.
- Everything should be sterile and single-use.
PRP vs PRF
PRP kits are designed to concentrate platelets in plasma, usually with an anticoagulant and specific spin settings. PRF kits produce a fibrin matrix without anticoagulant and are spun differently. Providers choose based on their protocols; many practices stock both.
Centrifuge validation
Kits are typically validated for specific centrifuges, speeds and spin times. Using a kit with the wrong centrifuge settings changes the result. Before you buy, confirm which centrifuges the manufacturer validates the kit for, and whether your existing centrifuge is on the list.
Regulatory status
PRP preparation systems and tubes are regulated as medical devices, and many are FDA-cleared through 510(k). Ask for the clearance documentation for the exact kit, and keep your marketing to the device's cleared use. Preparing PRP for a patient's own use at the point of care is a provider decision made under their license.
Cost per treatment
Add up the kit cost, any disposables not included, and your time per preparation. Kits that include everything often cost more per unit but reduce the chance of a missing item delaying a treatment.
Questions to ask your supplier
- Is the kit FDA-cleared, and for which centrifuges is it validated?
- What's included, and what do we need to buy separately?
- Are PRP and PRF versions available?
- What's the shelf life, and how many kits come per case?
Frequently asked questions
Do PRP kits work with any centrifuge?
No. Kits are validated for specific centrifuges and settings. Confirm compatibility before buying.
Are PRP kits FDA-cleared?
Many PRP preparation systems are FDA-cleared as devices. Ask for the documentation for the exact kit.
Can we set up a standing order for kits?
Yes. Most practices order kits monthly based on treatment volume.
Ready to price prp and prf kits?
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This guide is general product and purchasing information for licensed healthcare businesses. It isn't medical, legal or regulatory advice. Follow your medical director's protocols and the manufacturer's instructions.